Myocardial dysfunction as a component of multiple organ discrepancy with neonatal sepsis

The formation of myocardial dysfunction in neonatal sepsis remains a topical issue current practice. Myocardial with is found to promote double increase loss rate, and maintenance an adequate cardiac output very important predictor for survival patients sepsis. Purpose - study clinico-paraclinical markers case alternative term debut timely verification rational correction cardiovascular disorders. Materials methods. Considering various terms manifestation its early late variants, comparative analysis clinical-paraclinical generalized infectious-inflammatory process was made 26 neonates at the stage obstetrical aid (retrospective analysis) intensive care departments their resuscitation (prospective follow-up). According results medical records newborns, diagnosis established 14 (53.8%) newborns who were included clinical group I study, 12 (46.2%) II. Results. After birth general condition from assessed as moderate severity 1 (7.1%) severe 13 (92.9%) neonates; II 2 (16.7%) (р>0.05) 10 (83.3%) (р>0.05). Assessment constituent groups comparison according constellation scale nSOFA means values did not differ reliably, though it indicative tendency deeper disorders Conclusions. Sepsis-induced manifested by content cardio-specific (creatine phosphokinase, МВ fraction, troponin I). An increased blood higher than that norm possesses high inclination dysfunction. research carried out accordance principles Helsinki Declaration. protocol approved Local Ethics Committee participating institution. informed consent patient obtained conducting studies. No conflict interests declared authors. Keywords: neonates, sepsis,